Convulsion is an episode of abnormal violent and involuntary contraction of the muscle movements. It occurs when brain cells become too active and disorganized in their electrical properties. The plant is well known for its antiinflammatory, anticancer, antistress and immunomodulatory, adaptogenic, endocrine and cardiovascular activities In the present study, an attempt had been made to develop and evaluate the herbal orodispersible tablets of an alkaloid rich fraction of Withania somnifera Dunal of family Solanaceae which disperses in the oral cavity and give enhanced dissolution rate with improved patient compliance. The tablet weighing 100 mg was evaluated and tested for pharmaceutical characters. The dissolution rate was studied using 6.8pH Po4 buffer and 0.1N HCl for release time of 20 min.
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